Antimicrobial Resistance In Salmonellosis

TABLE OF CONTENT





PAGES


INTRODUCTION…………………………………………………………………………...... 1


1.1 SALMONELLOSIS…………………………………………………. 2


1.2.0 CLINICAL MANIFESTATION………………………………….. 3


1.2.1Typhoid fever………………………..…………………………….. 3


1.2.2 Paratyphoid fever………….……………………………………… 4


1.2.3 Human Gastroenteritis……………………………………………. 4


1.2.4 Food poisoning…..………………………………………………... 5


1.3.0 Scientific classification of Salmonella……………………………. 6


1.3.1 Salmonella………………………………………………………… 6


Salmonella as a pathogen……………………………………....... 7


1.4 Epidemiology……….……………………………………............... 7


1.5 Pathogenesis……….……………………………………………….. 8


1.6.0 Antimicrobial therapy of salmonellosis ………………………… 10


1.6.1 Mechanism of antimicrobial against Salmonella………………... 13


1.7.0 Antimicrobial resistance………………………………………….. 13


1.7.1 Origin of antimicrobial resistance……………………………...... 13


1.7.2 Spread of antimicrobial resistance………………………………. 14


Mechanism of antimicrobial resistance in salmonellosis………. 14


1.8.0 Antimicrobial susceptibility testing……………………………… 21


1.8.1 Specimen requirement…………………………………………… 22


1.8.2 Interpretation of result…………………………………………… 23


1.9.0 Treatment and Prevention……………………………………….. 24


1.9.1Treatment…………………………………………………………. 24


1.9.2 Prevention……………………………………………………....... 24


2.0 CONCLUSION and RECOMMENDATION…………………….. 25


REFRENCES………………………………………………………… 26-30