ABSTRACT
Inflammation is a complex biological response of vascular tissue to harmful stimuli such as pathogen, damage cells or irritants. The urgency generated by in increased rate of stroke, atheroselerosis attributed to prolong use of cyclooxygenase-1 and 2 inhibitors have acceralated anti-inflammatory drug research over the last decade while synthetic pharmaceutical agents continued to dominate research, attention increasingly has been directed to natural products. These are often more affordable and available and sometimes are perceived as more effective than conventional anti-inflammatory drugs.
Anti-inflammation was carried out using 11 rats. That was divided into three groups of four rats each. Group 1 and 2 served as the positive and negative control respectively. Groups 3 and 4 received 200mg/kg b.w and 600mg/kg b.w. of the extracts respectively. However, it was discovered that the stem bark of crateva Adansonii showed greater significance anti-inflammatory activity when compared with the standard.
TABLE OF CONTENTS
Title page - - - - - - - - i
Certificate page - - - - - - - ii
Dedication - - - - - - - - iii
Acknowledgment - - - - - - - iv
Abstract - - - - - - - - - v
Table of contents - - - - - - - vi
CHAPTER ONE
1.0 Introduction - - - - - - - 1
1.1 Types of inflammation - - - - - 2
1.2 Aims and objectives - - -- - - 3
1.3 Rational study - - - - - - - 3
1.4 Taxonomy - - - - - - - 4
1.5 Physical description of crateva adansonii - 5
1.6 Distribution - - - - - - - 6
1.7 Cultivation - - - - - - - 6
1.8 Uses of crateva adansonii - - - - 7
1.9 Sources - - - - - - - - 7
CHAPTER TWO
Literature review - - - - - - - 8
2.1 types of inflammation - - - - - 8
2.2 Events in acute inflammation - - - 22
2.3 Increased blood flow and from - - - 26
2.4 Chemotaxis - - - - - - - 26
2.5 Eosinophils - - - - - - - 27
2.6 Benefit of inflammation - - - - - 29
2.7 Anti-inflammation agents - - - - 30
2.8 Steroids - - - - - - - - 30
2.9 Non-steroidal anti-inflammation drugs (NSAIDS) 31
2.10 Immune Selective Anti-Inflammatory Derivatives (IMSAID) - - - - - - 33
2.11 Anti inflammatory diet - - - - 34
2.12 Natural anti-inflammatory supplements - 36
2.13 Benefits of non-sterodial anti- inflammatory 38
2.14 Mediators of information - - - - -39
2.15 Cytokines - - - - - - - 41
2.16 Histamine - - - - - - - 42
2.17 Arachidonic acid - - - - - - 42
2.18 Nitric oxide - - - - - - - 45
CHAPTER THREE
MATERIALS AND METHODS
3.1 Materials - - - - - - - - 47
3.2 Methodology - - - - - - - 49
3.4 Column chromatography - - - - 50
3.5 Phytochemical analysis of the extract - - 58
3.6 Thin layer chromatograophy (TLC) - - 62
3.7 Anti-inflammatory activity test - - - 63
3.8 Thin layer chromatography (TLC) - - - 65
CHAPTER FOUR
4.1 The effect of methanol fraction of methanol extract of crateva adansonii ion acute inflammation of rat paw.
4.2 Phytochemical analysis of extract - - - -68
4.3 Phytochemical analysis of dichloromethane fraction 69
CHAPTER FIVE
5.1 Discussion - - - - - - - -70
5.2 Conclusion - - - - - -
Disclaimer: Note this academic material is intended as a guide for your academic research work. Do not copy word for word. Note: For Computer or Programming related works, some works might not contain source codes
CITE THIS WORK
(2014, 07). Phytochemical Analysis And The Anti-inflammatory Activities Of Methanol Extract Of Crateva Adansonii.. ProjectStoc.com. Retrieved 07, 2014, from https://projectstoc.com/read/2366/phytochemical-analysis-and-the-anti-inflammatory-activities-of-methanol-extract-of-crateva-adansonii-4925
"Phytochemical Analysis And The Anti-inflammatory Activities Of Methanol Extract Of Crateva Adansonii." ProjectStoc.com. 07 2014. 2014. 07 2014 <https://projectstoc.com/read/2366/phytochemical-analysis-and-the-anti-inflammatory-activities-of-methanol-extract-of-crateva-adansonii-4925>.
"Phytochemical Analysis And The Anti-inflammatory Activities Of Methanol Extract Of Crateva Adansonii.." ProjectStoc.com. ProjectStoc.com, 07 2014. Web. 07 2014. <https://projectstoc.com/read/2366/phytochemical-analysis-and-the-anti-inflammatory-activities-of-methanol-extract-of-crateva-adansonii-4925>.
"Phytochemical Analysis And The Anti-inflammatory Activities Of Methanol Extract Of Crateva Adansonii.." ProjectStoc.com. 07, 2014. Accessed 07, 2014. https://projectstoc.com/read/2366/phytochemical-analysis-and-the-anti-inflammatory-activities-of-methanol-extract-of-crateva-adansonii-4925.
- Related Works
- Effect Of Different Organic And Inorganic Nitrogen Sources On The Kinetics Of The Breakdown Of Crude Oil Using Pseudomonas
- Phytochemical Screening And Invivo Antiplasmodial Activity Of Methanol Extract Of Baobab Leaves (adansonia Digitata)
- Phytochemical Analysis And The Anti-inflammatory Activities Of Methanol Extract Of Crateva Adansonii
- Cardio Protective Activities Of N-hexane Extract Of Desmodium Velutinum Stem On Albino Wister Rat.
- Antilipidemic Effect Of Water (h20) Extract Of Desmodium Velutinum Leaves On Albino Wistar Rats
- Bacteriological Assessment Of Drinking Water In Ankpa Local Government, Kogi State
- Effects Of Yoyo Bitters And Swedish Bitters On The Arylesterase Activity In Very Low Density Lipoprotein Of Male Albino Rats
- The Effect Of Water Extract Of Cola Nitida Pod On Lipoprotein Concentrations Of Albino Wistar Rats.
- The Anti-inflammatory Activity Of Crateva Adansonii Dichloromethane Fraction
- The Determination Of The Activities And Specificity Of Enzymes In Fermentation Of Starch-from Maize